Protein Trafficking Practice Test 2025 - Free Protein Trafficking Practice Questions and Study Guide

Viral protein trafficking primarily functions by hijacking host cell machinery. This mechanism is crucial for viruses as they do not possess the cellular structures necessary for their own protein synthesis and transport. Instead, viruses exploit the existing pathways and resources of the host cell to replicate and disseminate their proteins.

When a virus infects a host cell, it injects its genetic material, which is then transcribed and translated using the host cell's ribosomes, cellular machinery, and metabolic energy. This appropriation includes manipulating the host's endoplasmic reticulum and Golgi apparatus, which are typically involved in protein synthesis and post-translational modification. By taking control of these cellular processes, the virus can ensure that its proteins are synthesized, processed, and transported within the host cell effectively and efficiently.

While ATP is a source of energy for many cellular processes, and protein synthesis does occur in the cytoplasm, these mechanisms are secondary to the central role of hijacking host machinery in viral protein trafficking. The Golgi apparatus does play a role in the processing of some viral proteins, but the primary mechanism remains the exploitation of the host's cellular systems to achieve viral replication and assembly.