What happens to the protein after the SRP binds the ER signal sequence?

When the signal recognition particle (SRP) binds to the endoplasmic reticulum (ER) signal sequence of a nascent protein, its primary function is to direct the protein to the ER membrane. The binding of the SRP to the signal sequence halts translation temporarily and directs the ribosome-protein complex to the SRP receptor located on the ER membrane. This interaction facilitates the transfer of the ribosome and the growing polypeptide chain to a translocon, a channel in the ER membrane. Once at the translocon, the protein can continue its synthesis and be translocated into the lumen of the ER, marking the beginning of its proper trafficking pathway. Therefore, the binding of the SRP is crucial for ensuring that proteins destined for secretion or for the ER membrane itself are properly directed to the appropriate cellular compartment.